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PRINCIPAIS DIFERENCIAIS
- 1 cápsula ao dia1
- Fórmula composta por nutrientes que vão muito além do metilfolato1
- Metilfolato 2,3
- Forma biologicamente ativa do ácido fólico
- Sua metabolização não é afetada pelos distúrbios da enzima MTHFR
- Colina4-7
- Envolvida na maturação dos óvulos
- Trio de Antioxidantes1
- Zinco, vitamina E e vitamina C
- Vitamina D1
- 1000 UI de Vitamina D
- A vitamina D auxilia no funcionamento do sistema imune.
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REFERÊNCIAS
1.Folheto informativo Ogestan Pré. 2. OBEID R, HOLZGREVE W, PIETRZIK K. Is 5- methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects? J Perinat Med. 2013;41(5):469-83; 17. 3. LEEMANS L. Does 5-methyltetrahydrofolate offer any advantage over folic acid? J Pharm Belg. 2012;(4):16-22. 4. MCCLATCHIE, T. et al. Betaine is accumulated via transient choline dehydrogenase activation during mouse oocyte meiotic maturation. Journal of Biological Chemistry, v. 292, n. 33, p. 13784–13794, 18 ago. 2017. 5. BALTZ, J. M.; ZHOU, C. Cell volume regulation in mammalian oocytes and preimplantation embryos. Molecular Reproduction and Development, v. 79, n. 12, p. 821–831, dez. 2012. 6. ZHANG, B. et al. Both the folate cycle and betaine-homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts. The FASEB Journal, v. 29, n. 3, p. 1069–1079, mar. 2015. 7. LEE, M. B. et al. Betaine Homocysteine Methyltransferase Is Active in the Mouse Blastocyst and Promotes Inner Cell Mass Development. Journal of Biological Chemistry, v. 287, n. 39, p. 33094–33103, 21 set. 2012. 8. Folheto informativo do produto Ogestan Gold. 9. Wells ML, Potin P, Craigie JS et al. Algae as nutritional and functional food sources: revisiting our understanding. J Appl Phycol. 2017;29(2):949-98. 10. Agarwal A. Pareich N. Panner Selvam MK, et al Male Oxidative Stress infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility. Word J Mens Health. 2019 Sep; 37(3): 296-312. 11. Zegers-Hochschild F, Adamson GD, Dyer S, RacowskyC, de Mouzon J, Sokol R, et al. The internacional glossary on infertility and fertility care, 2017. Fetil Steril 2017; 108:393-406. 12. Esteves SC, Agarwal A. Novel concepts in male infertility. Int Braz J Urol 2011; 37(1):5-15. 13. Aitken RJ, Fisher H. Reactive oxygen species generation and human spermatozoa: the balance of benefit and risk. Bioassays 1994; 16:259–267. Disponível em: https://www.ncbi.nlm.nih.gov/pubmed/8031303. Acessado em 03/01/2020. 14. Saleh RA, Agarwal A. Oxidative Stress and Male Infertility: From Research Bench to Clinical Practice. Journal of Andrology 2002; 23(6):737-752. 15. Koppers AJ, De luliis GN, Finnie JM, et al. Significance of Mitochondrial Reactive Oxygen Species in the Generation of Oxidative Stress in Spermatozoa. J Clin Endocrinol Metabol 2008; 93:3199-3207. 16. De acordo com pesquisa realizada em 29/11/2019 com os seguintes produtos: Prefolin, Vitergan Zinco, Vitergan Master e Andractiv.
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